Solasodine is a major bioactive ingredient in Solanum nigrum L. that has strong\npharmacological characteristics. Therefore, the development of a simple and effective extraction\nmethod for obtaining solasodine is highly important. This study aims to provide a rapid and eective\nmethod for extracting solasodine from Solanum nigrum L. by microwave-assisted aqueous two-phase\nextraction (MAATPE). Methods: First, the high-performance liquid chromatography (HPLC)\nconditions were established for the detection of solasodine. Then, the aqueous two-phase system\n(ATPS) compositions were examined.Onthe basis of the results of single-factor experiments, for a better\nyield, response surface methodology (RSM) was used to optimize influential factors including the\nextraction temperature, extraction time and liquid-to-solid ratio...........................
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